Nick Pullen Selected Research

2- (4- (4- cyano- phenoxy)- 3,5- dicyclopropyl- 1H- pyrazol- 1- yl)- N- methylacetamide

10/2008

The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982).

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Nick Pullen Research Topics

Disease

3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 01/2016
3	Endometriosis 11/2011 - 10/2008
2	Fibrosis (Cirrhosis) 01/2022 - 08/2015
2	Chronic Renal Insufficiency 01/2022 - 01/2016
2	COVID-19 12/2021 - 10/2021
2	Proteinuria 01/2016 - 08/2015
2	Inflammation (Inflammations) 01/2016 - 08/2013
1	Infections 10/2021
1	Genomic Instability 01/2016
1	Acute Kidney Injury (Acute Renal Failure) 01/2016
1	Segmental glomerulosclerosis 01/2016
1	Reperfusion Injury 01/2016
1	Kidney Diseases (Kidney Disease) 01/2016
1	Vascular Remodeling 08/2013
1	Autoimmune Diseases (Autoimmune Disease) 08/2013
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2013
1	Hyperglycemia 08/2013
1	Insulin Resistance 08/2013
1	Autosomal Dominant Polycystic Kidney (ADPKD) 05/2012
1	Cysts 05/2012
1	Heart Failure 11/2011
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 11/2011
1	Liver Diseases (Liver Disease) 02/2011
1	Multiple Sclerosis 02/2010

Drug/Important Bio-Agent (IBA)

2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2016
2	AntibodiesIBA 10/2021 - 08/2013
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 02/2010
1	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	insulin receptor-related receptor (IRR)IBA 12/2021
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 12/2019
1	Messenger RNA (mRNA)IBA 01/2016
1	RibonucleoproteinsIBA 01/2016
1	ChromatinIBA 01/2016
1	Pharmaceutical PreparationsIBA 01/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2016
1	Cytokine TWEAKIBA 01/2016
1	TWEAK ReceptorIBA 01/2016
1	Thrombin FDA Link 08/2015
1	CreatinineIBA 08/2015
1	5- amino- 2- ((1- n- propyl- 1H- imidazol- 4- yl)methyl)pentanoic acidIBA 08/2015
1	tyrosine receptor (receptor, tyrosine)IBA 08/2013
1	Glucose (Dextrose)FDA LinkGeneric 08/2013
1	Phosphotransferases (Kinase)IBA 08/2013
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 08/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2013
1	Prostaglandins EIBA 05/2012
1	ProstaglandinsIBA 05/2012
1	Arginine Vasopressin (Argipressin)IBA 11/2011
1	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 11/2011
1	Progesterone Receptors (Progesterone Receptor)IBA 11/2011
1	Cell Adhesion Molecule-1IBA 02/2011
1	Cell Adhesion MoleculesIBA 02/2010
1	2- (4- (4- cyano- phenoxy)- 3,5- dicyclopropyl- 1H- pyrazol- 1- yl)- N- methylacetamideIBA 10/2008
1	Mifepristone (RU 486)FDA Link 10/2008

Therapy/Procedure

2	Nephrectomy 01/2022 - 08/2015
1	Home Nursing (Nursing, Home) 12/2021
1	Therapeutics 11/2011